By Francesco Collamati
This thesis makes a speciality of a singular radio-guided surgical procedure procedure for entire tumor resections. It describes all features of the intraoperative probe, in addition to trying out and simulation of the unconventional method. The presentation develops the procedure from the preliminary thought to practical feasibility experiences which were the topic of a statement of the yank Society of Nuclear drugs. only a yr after finishing this paintings, the strategy has now been verified for the 1st time on a meningioma sufferer, confirming all the predictions made during this thesis.
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Extra info for An Intraoperative Beta−Probe for Cancer Surgery
Chojniak, New applications of radioguided surgery in oncology. Clinics. 64, 397–402 (2009) 12. S. P. Baum, A. J. Wenisch, E. Staib-Sebler, G. Herrmann, A. Encke, G. Hör, Intraoperative gamma probe detection of neuroendocrine tumors. J. Nucl. Med. Off. Publ. Soc. Nucl. Med. 39, 1155–1160 (1998) 13. H. Chen, E. R. Starling, Radioguided parathyroidectomy is equally effective for both adenomatous and hyperplastic glands. Ann. Surg. 238, 332–337; discussion 337–338 (2003) 14. K. N. Aarsvold, Intraoperative probes.
The light emitted from the lamp was carried by an optical fiber to the front face of the investigated sample, housed in a devoted support. Another optical fiber, placed on the opposite side of the sample carries the transmitted light to the Spectrophometer. The obtained spectrum is showed in Fig. 17, together with the one in absence of the sample, to show the spectral components of the used UV lights. e. the edge of visible light, which is a zone commonly well covered by standard PMT, and also by the one used in the first prototypes.
19). For each point in the scanning and each probe configuration the rate was evaluated by means of the procedure described in Sect. 2. The results, normalized to the case without shielding, are showed in Fig. 20a–c. 20d shows the spatial resolution, obtained as the σ from a Gaussian fit to the spectra (considering the background as a constant in the examined range). The dotted lines represent (via the corresponding color) the actual thickness of the shielding for each existing probe prototype.