By Professor Klaus Kayser M.D., Ph.D. (auth.)
All illnesses concerning the lung are awarded in alphabetical order. each one is mentioned within the similar method less than the subheadings of definition, epidemiology, pathophysio- logy, medical diagnosis, radiology, gross and micro patho- logy, histomorphological descriptors, specified stains, corridor- mark of analysis and differential diagnosis.
"An encyclopedic choice of phrases facing illnesses and/or pathological stipulations of the respiration organs with the purpose to offer the reader fast information regarding the basic facets. This encyclopedic resource should be advised not just to pathologists but additionally to clinicians and practitioners confronted with pulmonary diseases." (Experimental and Toxicologic Pathology)
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Additional info for Analytical Lung Pathology
Acinar adenocarcinoma 2. papillary adenocarcinoma 3. bronchioloalveolar adenocarcinoma 4. solid adenocarcinoma The subclassification is, however, obscured by the fact that the majority of adenocarcinomas show mixtures of the different categories depending upon their differentiation. The grading of adenocarcinoma is divided as usual into three categories: well differentiated, moderately differentiated, and poorly differentiated adenocarcinoma. The acinar, papillary, and solid adenocarcinomas consist of medium-sized to large tumor cells with prominent nucleoli in the nuclear chromatin.
Size of the adiaconidia 200-500 Ilm, thickness of the wall 20-70 Ilm. The adiaconidia are embedded in granulomatous tissue with concentrically arranged fibroblasts, collagen fibers, and scattered giant cells. The adjacent lung tissue is unsuspicious. ~ Descriptors: Lung parenchyma with altered structure: • noncaseous epithelioid granulomas • fungus (intragranulomatous, adiaspores) • multinucleated giant cells • palisading histiocytes • focal interstitial fibrosis • Special stains: PAS, Mayer's mucicarmine technique, Gridley, gallocyanin, toluidine blue.
Type II: (intermediate type) smaller, more uniform cysts (5-20 mm) resembling numerous ectatic, overlying bronchioles. 32 Type III: (solid type) curved channels or randomly distributed bronchiole-like cystic structures ( 1-3 mm) lined with cuboidal epithelium. IncidencelEpidemiology: Relatively common with slight predominance in men. Type I is the most frequent (approximately 65%), followed by type II (approximately 25%), and by type III (approximately 10%). Etiology/Pathophysiology: The more mature type I lesion suggests an onset at 7-10 weeks' gestation in contrast to the more immature type II lesion (estimated onset 3--4 weeks' gestation).