By Edouard Kurstak (Auth.)

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This conviction would have to be based on vaccinating a higher proportion of cattle at risk than is usual. In such a situation, the cost-to-benefit equation for control would include the extra cost of reaching all livestock in the given area, but it would also include the extra benefit of greatly reduced virus transmission. This worldwide situation, marked by the need for very large numbers of vaccine doses, for vaccine of increased potency (so as to reduce immunization frequency), for vaccine which is absolutely incapable of causing disease (inadequate inactivation has been a common problem in vaccine manufacture), and for vaccine which is inexpensive, has been addressed by bioengineering technology.

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